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Investigators in Japan studied 145 patients who developed HHV-6 encephalitis.
At 100 days after transplantation, the overall survival rate was just 58.3%, compared with 80.5% for patients who did not develop encephalitis.
Swedish investigators have found HHV-6 protein in the pancreatic islet cells of both type 1 diabetes patients and controls.
The viral load was higher in the islet cells than in surrounding tissues.
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HIV patients on antiretrovrial therapy with high levels of HHV-6 shedding had lower levels of IL-6 and other inflammatory markers.
While HIV patients had increased shedding of EBV and CMV, there was no difference in shedding between patients and controls for HHV-6.
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